Description
Product Characteristics: For the quantitative determination of human proteolysis inducing factor/dermcidin (PIF/DCD) concentrations in serum, plasma, cell culture supernates, urine, tissue homogenates.
Target Information: This gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. [provided by RefSeq, Jul 2008]